Pentostatin administration requires an experienced clinician who is qualified and knowledgeable in the use of cancer chemotherapeutic agents. The use of higher than the FDA-approved dosage is not recommended; severe nephrotoxicity, hepatotoxicity, pulmonary toxicity, and neurotoxicity occurred with pentostatin 20 to 50 mg/m2 administered in divided doses over 5 days in a phase 1 study.

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COMMON BRAND NAME(S): Nipent . WARNING: The use of doses higher than specified by the manufacturer is not recommended. Severe kidney, liver, lung, and central nervous system problems (toxicities) have occurred in some studies when using higher than recommended doses. This drug is not recommended for use with fludarabine.

Nipent package insert

Indication. • Hairy cell leukaemia. Toxicity. Drug.

Nipent [package insert]. Lake Forest, IL: Hospira, Inc.;2009 April. Pentostatin. Drug Facts and Comparisons. Drug Facts and Comparisons 4.0 [online]. 2012.

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Package Insert For in-vitro diagnostic use Availability of individual reports may be subject to product purchased. Table of contents Genetic Health Risk Intended use Important warnings and limitations Test performance User studies Specific test information BRCA1/BRCA2 (Selected Variants) Indications for use

See full prescribing information for A package insert is a document included in the package of a medication that provides information about that drug and its use.

PDF (1 MB) May 6, 2020. VeriSeq NIPT Solution Package Insert translated into German. PDF (< 1 MB) May 6, 2020. VeriSeq NIPT Solution Package Insert translated into Italian. PDF (< 1 MB) May 6, 2020. VeriSeq NIPT Solution Package Insert translated into Portuguese.
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Cartridges; NIPENT vials are stable at refrigerated storage temperature 2° to 8° C (36° to 46°F) for the period stated on the package. Vials reconstituted or reconstituted and further diluted as directed may be stored at room temperature and ambient light but should be used within 8 hours because NIPENT contains no preservatives. Nipent (pentostatin) Non-Oncology Policy (Intravenous) Department: PHA Effective Date: 09/01/2020 Review Date: 8/3/2020 Revision Date: Purpose: To support safe, effective and appropriate use of Nipent (pentostatin). Scope: Medicaid, Commerical, Medicare-Medicaid Plan (MMP) Policy Statement: Nipent Powder works by slowing or stopping the growth of cancer cells in the body.

Detailed information related to Nipent Powder's uses, composition, dosage, side effects and reviews is listed below.
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The mean values printed in this insert were derived from replicate analyses and are specific for this lot of product. The tests listed were performed by the reagent manufacturer and/or independent laboratories using manufacturer supported reagents and a representative sampling of this lot of control.

Nipent (pentostatin for injection) is supplied as a sterile lyophilized white to off-white powder in single-dose vials containing 10 mg of pentostatin. The vials are packed in individual cartons.

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NIPENT vials are stable at refrigerated storage temperature 2° to 8° C (36° to 46°F) for the period stated on the package. Vials reconstituted or reconstituted and further diluted as directed may be stored at room temperature and ambient light but should be used within 8 hours because NIPENT contains no preservatives.

Administering/wasting from unit-dose package Nipent . Perjeta, Phesgo. N/A. Polivy. Pemazyre. Folotyn. Matulane.